Preeclampsia a pregnancy specific syndrome is one of the most common causes of maternal and fetal morbidity and mortality. It’s exact etiology is not known, but it may be associated with alteration in electrolytes status. Aim of the study to evaluate role of serum calcium, sodium, potassium and chloride in preeclampsia and to compare them with those in normal pregnancy. It was a comparative cross sectional study conducted at the Department of Biochemistry, Sylhet Women’s Medical College Hospital from June 2019 to August 2019. Patients attending in the obstetrics and gynaecology outpatient department were invited to participate in the study. A total of 60 subjects were involved in the study. The study subject comprised of two groups. Thirty were preeclamptic women considered as group-I and 30 were normotensive pregnant women considered as group-II. Serum calcium, sodium, potassium and chloride were analyzed in two groups. The results showed that, serum calcium, potassium were significantly decreased (P<0.001) and serum sodium, chloride were significantly increased (P<0.001) in preeclamptics as compared to normal pregnant women. It may be concluded that, dietary restriction of sodium, a dietary supplementation of calcium and potassium in the form of milk, cheese, soybean products, leafy vegetables, etc. during pregnancy, could result in a reduction in the incidence of pregnancy induced hypertension.

Keywords: Calcium, Sodium, Potassium, Chloride, Preeclampsia.